NEW TREATMENT REGIMEN FOR MULTI- DRUG RESISTANT-TUBERCULOSIS (MDR – TB)

The Ministry of Health and Family Welfare approved a new BPaLM regimen consisting of four drugs Bedaquiline, Pretomanid, Linezolid and Moxifloxacin — has proven to be a safe, more effective and quicker treatment option than previous procedures.

  • Earlier, Pretomanid has been approved & licensed for use in India by CDSCO.
  • It brings down treatment time to 6 months from the earlier duration of 20 months.
  • BPaLM regimen was introduced under National TB Elimination Programme and expected to boost the country’s progress to achieve its national goal of ending TB in India by 2025.

About Tuberculosis

  • An infectious disease that most often affects lungs and is caused by bacillus Mycobacterium tuberculosis bacteria.
  • Bacillle Calmette-Guerin (BCG) vaccine provides immunity against TB.

Types of Drug – Resistant TB 

  • Multidrug Resistance TB (MDR) : Resistant to Isoniazid and Rifampin
  • Extensively drug Resistance tuberculosis TB (XDR-TB)

Resistant to Isoniazid and Rifampin plus any fluoroquinolone and at least one of three injectable second-line drugs (amikacin, kanamycin, or capreomycin)

  • Totally drug-resistant tuberculosis (TDR-TB)

Resistant to all first- and second-line TB drugs.

Other Initiatives taken for Tuberculosis Eradication 

  1. Pradhan Mantri TB Mukt Bharat Abhiyan provides additional patient support, augment community involvement.
  2. Ni-kshay Mitra ensures additional diagnostic, nutritional, support to those on TB treatment.
  3. Nikshay Poshan Yojana provides financial support to TB patients for their nutrition.

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